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. Author manuscript; available in PMC: 2024 Mar 1.
Published in final edited form as: Adv Mater. 2023 Jan 11;35(10):e2208781. doi: 10.1002/adma.202208781

Figure 5. MSCM-coating synergized with BMP-2 to enhance new bone formation, angiogenesis and stem cell recruitment in vivo.

Figure 5.

(a) Representative μCT images and percentage of newly formed bone volume in the mouse cranial defects at week 2 and week 6. (c) Representative morphology of newly formed bone at week 6, as shown by H&E staining. White triangles mark the edges of the defect. Scale bar: 1 mm in low magnification images, 100 μm in high magnification images. (d) Representative TRAP staining images for osteoclasts at week 6. (e, f) Representative immunofluorescent staining images and quantification of CD31+ endothelial cells (e) and CD90+ MSCs (f) in the cranial defects at week 6. Scale bar in (e, f): 100 μm. Data are represented as mean ± S.D. (n = 5). ****P < 0.0001.