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. 2023 Mar 1;16(3):376. doi: 10.3390/ph16030376

Figure 7.

Figure 7

The mutational perspective of BVDV-RdRp. The palm, thumb, and finger domains are shown in the new cartoon representation, and colored in dark yellow, orange, and purple, respectively. The N-terminal and fingertip regions are shown in blue and cyan, respectively. Resistant mutations of different classes of NNIs, residues F224 (in loop L2), E291 (near the fingertip), N264 (in motif I of the fingertip), A392 (in loop L1), and I261 (in motif I of the fingertip) of 227G, are rendered in VDW and colored in gray and green, respectively. The location of resistant mutations is indicated by black arrows.