Table 8.
The values of inflammation-related parameters at the beginning (V1) and the end (V2) of the pilot study.
| Parameter [mean ±SD] |
V1 PRO-D | V2 PRO-D | Δ [95% CI] |
V1 PLC-D | V2 PLC-D | Δ [95% CI] |
V1 PRO-DMS | V2 PRO-DMS | Δ [95% CI] |
V1 PLC-DMS | V2 PLC-DMS | Δ [95% CI] |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CRP (mg/L) | 2.17 ± 1.88 |
1.53 ± 1.24 |
−0.64 [−1.66, 0.38] |
1.91 ± 2.34 |
2.18 ± 2.03 |
0.27 [−0.59, 1.13] |
2.97 ± 1.72 |
2.53 ± 1.98 |
−0.43 [−1.51, 0.65] |
4.32 ± 2.48 |
3.88 ± 2.04 |
−0.44 [−5.18, 4.30] |
| WBC (×103/µL) | 5.88 ± 1.41 |
5.99 ± 1.51 |
0.11 [−0.44, 0.66] |
5.87 ± 1.07 |
6.13 ± 1.19 |
0.26 [−0.25, 0.77] |
5.52 ± 1.02 |
5.63 ± 1.53 |
0.11 [−0.57, 0.79] |
7.29 ± 1.97 |
7.41 ± 1.72 |
0.12 [−1.49, 1.72] |
| NEU (×103/µL) | 3.23 ± 1.16 |
3.29 ± 1.15 |
0.05 [−0.42, 0.52] |
3.06 ± 0.65 |
3.29 ± 0.73 |
0.23 [−0.19, 0.66] |
2.80 ± 0.58 |
2.94 ± 0.85 |
0.14 [−0.19, 0.465] |
4.22 ± 1.48 |
4.13 ± 0.99 |
−0.09 [−1.19, 1.01] |
| LYM (×103/µL) | 1.83 ± 0.57 |
1.93 ± 0.55 |
0.09 [−0.07, 0.26] |
2.09 ± 0.51 |
2.13 ± 0.54 |
0.04 [−0.20, 0.28] |
2.04 ± 0.48 |
1.97 ± 0.54 |
−0.06 [−0.35, 0.23] |
2.23 ± 0.47 |
2.37 ± 0.64 |
0.15 [−0.45, 0.75] |
| NEU /LYM |
2.02 ± 1.42 |
1.81 ± 0.74 |
−0.20 [−0.78, 0.38] |
1.55 ± 0.49 |
1.63 ± 0.43 |
0.08 [−0.20, 0.36] |
1.43 ± 0.34 |
1.51 ± 0.26 |
0.09 [−0.06, 0.23] |
1.91 ± 0.50 |
1.80 ± 0.38 |
−0.11 [−0.68, 0.46] |
| PLT | 271.47 ± 43.75 |
259.11 ± 47.68 |
−12.37 [−22.42, −2.32] |
279.27 ± 45.05 |
275.53 ± 56.05 |
−3.73 [−18.42, 10.95] |
299.17 ± 112.62 |
303.33 ± 105.85 |
4.17 [−15.34, 23.67] |
288.83 ± 60.42 |
305.33 ± 39.62 |
16.50 [−23.35, 56.35] |
| PLT /LYM |
161.27 ± 48.84 |
145.99 ± 48.43 |
−15.29 [−36.77, 6.20] |
142.14 ± 38.89 |
136.14 ± 30.37 |
−6.00 [−23.41, 11.41] |
148.57 ± 44.56 |
158.29 ± 43.53 |
9.72 [−18.29, 37.72] |
124.22 ± 9.79 |
130.14 ± 34.21 |
5.92 [−38.95, 50.79] |
| SII | 541.55 ± 344.05 |
482.12 ± 235.55 |
−59.42 [−199.08, 80.23] |
432.21 ± 136.94 |
448.70 ± 133.64 |
16.49 [−70.82, 103.79] |
404.27 ± 101.82 |
439.22 ± 82.38 |
34.95 [−0.55, 70.45] |
522.24 ± 174.18 |
521.77 ± 104.44 |
−0.47 [−227.57, 226.62] |
PRO-DMS: probiotic + depression + MetS group; PRO-D: probiotic + depression group; PLC-DMS: placebo + depression + MetS group; PLC-D: placebo + depression group; CRP: C-reactive protein; WBC: white blood cells; NEU: neutrophils; LYM: lymphocytes; PLT: platelets; SII: systemic inflammatory index.