Table 5.
Histologic findings in the lungs of bank voles from OS affected with Hepatozoon spp., Emmonsia crescens or both pathogens.
| RT-PCR Pos ELISA Pos (Persistent Infection) |
RT-PCR Pos ELISA Neg (Acute Infection) |
RT-PCR Neg ELISA Pos |
Pathogen | |
|---|---|---|---|---|
| Total | 23/29 (79%) 12/23 M, 11/23 F |
3/3 (100%) 2/3 M, 1/3 F |
3/4 (75%) 3/3 M |
Hepatozoon spp. |
| 1/29 (3%) 1/1 F |
0/3 (0%) | 0/4 (0%) | E. crescens | |
| 4/29 (14%) 2/4 M, 2/4 F |
0/3 (0%) | 0/4 (0%) |
Hepatozoon spp. and E. crescens |
|
| Desquamated alveolar macrophages | 6/23 (26%) | 1/3 (33) | 1/4 (25%) | Hepatozoon spp. |
| Interstitial infiltrates: mononuclear cells * | 1/23 (4%) | 0/3 (0%) | 1/4 (25%) | |
| Interstitial infiltrates: mononuclear cells, BALT-hyperplasia * | 1/23 (4%) | 0/3 (0%) | 0/4 (0%) | |
| Interstitial infiltrates: mononuclear cells, neutrophils * | 10/23 (44%) | 0/3 (0%) | 0/4 (0%) | |
| Interstitial infiltrates: mononuclear cells, neutrophils, syncytia * | 0/23 (0%) | 1/3 (33) | 0/4 (0%) | |
| Interstitial infiltrates: mononuclear cells, neutrophils, eosinophils * | 1/23 (4%) | 1/3 (33) | 0/4 (0%) | |
| Interstitial infiltrates: mononuclear cells, neutrophils, eosinophils, syncytia * | 1/23 (4%) | 0/3 (0%) | 0/4(0%) | |
| Interstitial pneumonia, neutrophils, syncytia * | 1/23 (4%) | 0/3 (0%) | 1/4 (25%) | |
| Desquamated alveolar macrophages | 1/28 (4%) | 0/3 (0%) | 0/3 (0%) | E. crescens |
| Desquamated alveolar macrophages | 1/4 (25%) | 0/3 (0%) | 0/3 (0%) |
Hepatozoon spp. and E. crescens |
| Interstitial infiltrates: mononuclear cells, neutrophils | 1/4 (25%) | 0/3 (0%) | 0/3 (0%) | |
| Interstitial infiltrates: mononuclear cells, neutrophils, eosinophils * | 1/4 (25%) | 0/3 (0%) | 0/3 (0%) |
*, findings accompanied by desquamated alveolar macrophages; M, males; F, females.