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Protective effect of COSs and NACOs against acrolein-induced ARPE-19 cell death. The cells were pretreated with 200, 400, 800 μM COSs (A) or NACOs (B) for 48 h and then treated with 75 μM acrolein for an additional 24 h. Cell viability was analyzed using the MTT method. Values are mean ± SD of five separate experiments. ## p < 0.01 vs. control (no acrolein, no COSs or NACOs); * p < 0.05, ** p < 0.01 vs. acrolein.
