Abbreviation	Description
API	Active pharmaceutical ingredient
DLS	Dynamic light scattering
ELSD	Evaporative light scattering detector
FEP	Fluorinated ethylene propylene
FID	Flame ionisation detector
GC	Gas chromatography
HPLC	High-performance liquid chromatography
HPMC E3	Hydroxypropyl methylcellulose E3
ICH	International Council for Harmonisation
MW	Molecular weight
MWCO	Molecular weight cut-off
OSN	Organic solvent nanofiltration
PET	Polyethylene terephthalate
PSD	Particle size distribution
PTFE	Polytetrafluoroethylene
PXRD	Powder X-ray diffractometer
rpm	Revolution per minute
Symbols	Description
$A_m$	Effective membrane area
$\mathsf{\Delta }t$	Time interval
$\mathsf{\Delta }m$	Change in mass
$w_E^P$	Mass fraction of ethanol in the permeate
$w_E^R$	Mass fraction of ethanol in retentate
$w_w^P$	Mass fraction of water in permeate
$w_w^R$	Mass fraction of water in retentate
Dv10	Volume-based diameter of 10% of the sample
Dv50	Volume-based diameter of 50% of the sample
Dv90	Volume-based diameter of 90% of the sample