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. 2023 Feb 24;15(3):627. doi: 10.3390/v15030627

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Comparison of specific memory B-cells (MBCs, top left) and IgG+ MBC (top right), IgM+ MBCs (bottom left), and IgA+ MBCs (bottom right) isotypes between the different subgroups at baseline (BL) and after two doses of vaccine (PV, post-vaccination). No CR (unexposed without cross-reactivity, green dots and bars), CR (unexposed with cross-reactivity, rose dots and bars), and Conv (convalescent, red dots and bars). Frequencies are indicated at the X axis. Statistically significant when p < 0.05. * = p < 0.05, ** = p < 0.01, and *** = p < 0.001.