Table 1.
Unexposed without Cross-Reactivity (No CR, N = 26) |
Unexposed with Cross-Reactivity (CR, N = 59) |
|||
---|---|---|---|---|
Convalescent (Conv, N = 64) |
ANOVA p |
|||
Age (years) | 44 (26–63) | 46 (24–66) | 41 (26–67) | 0.184 |
Sex (Female) | 20 (77%) | 41 (70%) | 41 (64%) | 0.36 0.392 |
Body Mass Index | 22.5 (20–27) | 23.6 (21–26.2) | 23.6 (22–26.8) | |
Obesity (>30) | 50 (13%) | 4 (7%) | 8 (13%) | |
Smoking | 3 (12%) | 19 (32%) | 25 (39%) | 0.005 |
Diabetes mellitus | 1 (4%) | 3 (5%) | 0 | 0.098 |
Hypertension | 0 | 6 (10%) | 6 (9%) | 0.781 |
Days from COVID-19 to inclusion | - | - | 198 (179–216) | - |
Serology at inclusion: | ||||
Anti-N IgG positive (N) | 0 | 0 | 37 (58%) | <0.001 |
IgG antibody titer (AU/mL) | 4.6 (4–6.3) | 4.66 (3.7–6.1) | 10.1 (5.3–19.8) | <0.001 |
Neutralizing antibodies (ng/mL) | - | - | 1692 (1004–2562) | |
Anti-S T-cell response: | ||||
CD4+ T-cell positive (N) | 0 | 35 (59%) | 33 (52%) | 0.792 |
CD8+ T-cell positive (N) | 0 | 31 (53%) | 28 (44%) | 0.570 |