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. 2023 Mar 13;12(6):2226. doi: 10.3390/jcm12062226

Table 1.

Characteristics of patients with different allergic conditions.

Characteristics All Patients
(n = 1273)
Any Single Allergic Disease
(n = 681)
Allergic Multimorbidities
(n = 592)
p Value
Gender, n (%) 0.005
Male 659 (51.8) 327 (48.0) 332 (56.1)
Female 614 (48.2) 354 (52.0) 260 (43.9)
Age, median [IQR] 13.0 [6.0; 28.0] 21.0 [7.0; 31.0] 10.0 [5.0; 23.2] <0.001
Age groups, n (%) <0.001
0–3 years 54 (4.2) 23 (3.4) 31 (5.2)
3–6 years 224 (17.6) 106 (15.6) 118 (19.9)
6–12 years 324 (25.5) 143 (21.0) 181 (30.6)
12–18 years 81 (6.4) 38 (5.6) 43 (7.3)
18–60 years 574 (45.1) 361 (53.0) 213 (36.0)
≥60 years 16 (1.3) 10 (1.5) 6 (1.0)
Number of diagnoses, mean (SD) 1.6 (0.8) 1.0 (0.0) 2.3 (0.6) <0.001
Allergic diseases, n (%)
AR 808 (63.5) 314 (46.1) 494 (83.4) <0.001
AS/CVA 240 (18.9) 51 (7.5) 189 (31.9) <0.001
AD/eczema 469 (36.8) 223 (32.7) 246 (41.6) 0.001
FA 224 (17.6) 62 (9.1) 162 (27.4) <0.001
AC 224 (17.6) 3 (0.4) 221 (37.3) <0.001
DA 54 (4.2) 28 (4.1) 26 (4.4) 0.914
Anaphylaxis 20 (1.6) 0 (0.0) 20 (3.4) <0.001
Allergen sIgE positivity, n (%) a 838 (85.1) 365 (79.0) 473 (90.4) <0.001
Inhaled allergens positivity, n (%) b 794 (82.2) 346 (76.2) 448 (87.5) <0.001
Ingested allergens positivity, n (%) b 181 (38.3) 56 (27.2) 125 (46.8) <0.001
tIgE level, median [IQR] 216.0 [86.4; 519.0] 136.0 [65.8; 338.0] 359.0 [166.0; 810.0] <0.001

Abbreviations: sIgE, specific immunoglobulin E; tIgE, total immunoglobulin E; SD, standard deviation; AR, allergic rhinitis; AS, asthma; CVA, cough variant asthma; AD, atopic dermatitis; FA, food allergy; AC, allergic conjunctive; DA, drug allergy. a During the investigation, 985 patients with allergic diseases were detected for allergen sIgE; among them, 462 only had one allergic disease and 523 were allergic multimorbidity. b During the investigation, 966 patients of all were detected for inhaled allergen sIgE; among them, 454 had one allergic disease and 512 were allergic multimorbidity. Overall, 473 patients were detected for ingested allergen sIgE, with 206 having a single entity and 267 having allergic multimorbidity.