Table 1.
Characteristics | All Patients (n = 1273) |
Any Single Allergic Disease (n = 681) |
Allergic Multimorbidities (n = 592) |
p Value |
---|---|---|---|---|
Gender, n (%) | 0.005 | |||
Male | 659 (51.8) | 327 (48.0) | 332 (56.1) | |
Female | 614 (48.2) | 354 (52.0) | 260 (43.9) | |
Age, median [IQR] | 13.0 [6.0; 28.0] | 21.0 [7.0; 31.0] | 10.0 [5.0; 23.2] | <0.001 |
Age groups, n (%) | <0.001 | |||
0–3 years | 54 (4.2) | 23 (3.4) | 31 (5.2) | |
3–6 years | 224 (17.6) | 106 (15.6) | 118 (19.9) | |
6–12 years | 324 (25.5) | 143 (21.0) | 181 (30.6) | |
12–18 years | 81 (6.4) | 38 (5.6) | 43 (7.3) | |
18–60 years | 574 (45.1) | 361 (53.0) | 213 (36.0) | |
≥60 years | 16 (1.3) | 10 (1.5) | 6 (1.0) | |
Number of diagnoses, mean (SD) | 1.6 (0.8) | 1.0 (0.0) | 2.3 (0.6) | <0.001 |
Allergic diseases, n (%) | ||||
AR | 808 (63.5) | 314 (46.1) | 494 (83.4) | <0.001 |
AS/CVA | 240 (18.9) | 51 (7.5) | 189 (31.9) | <0.001 |
AD/eczema | 469 (36.8) | 223 (32.7) | 246 (41.6) | 0.001 |
FA | 224 (17.6) | 62 (9.1) | 162 (27.4) | <0.001 |
AC | 224 (17.6) | 3 (0.4) | 221 (37.3) | <0.001 |
DA | 54 (4.2) | 28 (4.1) | 26 (4.4) | 0.914 |
Anaphylaxis | 20 (1.6) | 0 (0.0) | 20 (3.4) | <0.001 |
Allergen sIgE positivity, n (%) a | 838 (85.1) | 365 (79.0) | 473 (90.4) | <0.001 |
Inhaled allergens positivity, n (%) b | 794 (82.2) | 346 (76.2) | 448 (87.5) | <0.001 |
Ingested allergens positivity, n (%) b | 181 (38.3) | 56 (27.2) | 125 (46.8) | <0.001 |
tIgE level, median [IQR] | 216.0 [86.4; 519.0] | 136.0 [65.8; 338.0] | 359.0 [166.0; 810.0] | <0.001 |
Abbreviations: sIgE, specific immunoglobulin E; tIgE, total immunoglobulin E; SD, standard deviation; AR, allergic rhinitis; AS, asthma; CVA, cough variant asthma; AD, atopic dermatitis; FA, food allergy; AC, allergic conjunctive; DA, drug allergy. a During the investigation, 985 patients with allergic diseases were detected for allergen sIgE; among them, 462 only had one allergic disease and 523 were allergic multimorbidity. b During the investigation, 966 patients of all were detected for inhaled allergen sIgE; among them, 454 had one allergic disease and 512 were allergic multimorbidity. Overall, 473 patients were detected for ingested allergen sIgE, with 206 having a single entity and 267 having allergic multimorbidity.