Figure 23.

The A-FLIGHT-UR acronym may be utilized as an aid in remembering the multiple risk factors and metabolic toxicities associated with the MetS reloaded. This modified and updated table is provided with permission by CC 4.0 [12]. AGE = advanced glycation end products; ALE = advance lipoxidation end products; FOCM = folate one-carbon metabolism; HDL-C = high density lipoprotein-cholesterol; HPA = hypothalamic pituitary adrenal; Il-6 = interleukin-6; HDL = high-density lipoprotein; LDL-C = low-density lipoprotein-cholesterol; PKC = protein kinase C; RAGE = receptor or AGE; TNFα = tumor necrosis alpha.