Table 4.
Minimal inhibitory and fungicidal concentration (MIC and MFC) of ethanolic leaf extract, hexane fraction, and 11 isolated compounds of X. stuhlmannii.
| Yeasts Strains | |||||
|---|---|---|---|---|---|
| Tested Substances | Parameters | CA | CK | CP | CN |
| Leaf extract | MIC | >500 | >500 | >500 | >500 |
| MFC | ND | ND | ND | ND | |
| MFC/MIC | ND | ND | ND | ND | |
| 12 | MIC | >125 | 62.5 | 125 | 125 |
| MFC | ND | 250 | 250 | 250 | |
| MFC/MIC | ND | 4 | 2 | 2 | |
| 3 | MIC | 125 | >125 | 62.5 | 125 |
| MFC | 250 | ND | 250 | 250 | |
| MFC/MIC | 2 | ND | 4 | 2 | |
| 6 | MIC | >125 | >125 | 125 | 125 |
| MFC | ND | ND | 250 | 250 | |
| MFC/MIC | ND | ND | 2 | 2 | |
| 8 | MIC | 62.5 | 125 | >125 | >125 |
| MFC | 250 | 250 | ND | ND | |
| MFC/MIC | 4 | 2 | ND | ND | |
| 2 | MIC | >125 | 125 | >125 | 125 |
| MFC | ND | 250 | ND | 250 | |
| MFC/MIC | ND | 2 | ND | 2 | |
| Hexane fraction | MIC | >500 | >500 | 125 | >500 |
| MFC | ND | ND | 250 | ND | |
| MFC/MIC | ND | ND | 2 | ND | |
| 13 | MIC | >125 | 125 | >125 | >125 |
| MFC | ND | 250 | ND | ND | |
| MFC/MIC | ND | 2 | ND | ND | |
| 11 | MIC | >125 | 125 | 125 | >125 |
| MFC | ND | 250 | 250 | ND | |
| MFC/MIC | ND | 2 | 2 | ND | |
| Nysta | MIC | 0.5 | 0.25 | 1 | 0.25 |
| MFC | 2 | 1 | 2 | 1 | |
| MFC/MIC | 4 | 0.25 | 2 | 0.25 | |
Values are expressed (in µg/mL) as means ± SEM. Minimum inhibitory concentrations (MIC); Minimum fungicidal concentrations (MFC). CA: Candida albicans, CK: Candida krusei, CP: Candida parasilosis, CN = Cryptococcus neoformans; Nysta: Nystatin.