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. 2023 Feb 23;22(4):100518. doi: 10.1016/j.mcpro.2023.100518

Fig. 5.

Fig. 5

Proteins that contain inconsistent peptides. Each protein illustrates how quantitation methods are not designed to handle sparse data. The protein in panel A only contains inconsistent peptides and will be quantified differently depending on the summarization method used. The proteins in B and C illustrate that filtering out inconsistent peptides will drastically alter the results of quantitation.