Table 1.
Any-grade treatment-related and TEAEs, regardless of causality
| Event | Overall population (n = 68) |
|---|---|
| Any-grade TRAE (5% or over) | 53 (77.9%) |
| ECG QT prolonged | 36 (52.9%) |
| Nausea | 18 (26.5%) |
| Differentiation syndrome | 11 (16.2%) |
| Vomiting | 11 (16.2%) |
| Diarrhoea | 7 (10.3%) |
| Decreased appetite | 5 (7.4%) |
| Dysgeusia | 5 (7.4%) |
| Any-grade TEAE (20% or over) | 67 (98.5%) |
| ECG QT prolonged | 38 (55.9%) |
| Nausea | 34 (50.0%) |
| Vomiting | 27 (39.7%) |
| Febrile neutropenia | 21 (30.9%) |
| Diarrhoea | 20 (29.4%) |
| Fatigue | 18 (26.5%) |
| ALT increased | 17 (25.0%) |
| Headache | 16 (23.5%) |
| Hyperphosphataemia | 16 (23.5%) |
| Hypokalaemia | 15 (22.1%) |
| Hyponatraemia | 15 (22.1%) |
| Thrombocytopenia | 15 (22.1%) |
| Epistaxis | 14 (20.6%) |
| Peripheral oedema | 14 (20.6%) |
All AEs shown as n (%).
ALT, alanine aminotransferase.