Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Mar 29;14(3):224. doi: 10.1038/s41419-023-05709-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — A The Venn plot of proteome and RNA-seq revealed 5309 genes had significant alterations at the mRNA and protein levels after Aurora-A knockdown. B KEGG analysis of 5309 genes showed significant alterations in both proteome and RNA-seq. Glycolysis pathway can be remarkably enriched. C Analysis of TCGA database revealed Aurora-A was positively correlated with the glycolysis pathway. D Volcano plot highlighting phosphorylation changes of proteins. 318 proteins with 423 sites were identified with greater than 1.5-fold change in Aurora-A knockdown relative to control TPC-1 cells and plotted in red (upregulation) or blue (downregulation), respectively. E KEGG analysis of the phosphorylation-changed proteins after Aurora-A knockdown in TPC-1 cells. The glycolysis pathway was significantly enriched.