Table 2.
Proportion of female MS patients taking one or more drugs not recommended during pregnancy according to at least one database.
| No. of drugs with potential risk for the foetus | Total patient cohort (n = 212) |
Patients using contraceptivesa
(n = 101) |
Patients using no contraceptivesa
(n = 111) |
p Chi |
|---|---|---|---|---|
| 0 | 14 (6.6%) | 2 (2.0%) | 12 (10.8%) | <0.001** |
| 1 | 39 (18.4%) | 6 (5.9%) | 33 (29.7%) | |
| 2 | 50 (23.6%) | 17 (16.8%) | 33 (29.7%) | |
| 3 | 41 (19.3%) | 23 (22.8%) | 18 (16.2%) | |
| 4 | 29 (13.7%) | 21 (20.8%) | 8 (7.2%) | |
| ⩾5 | 39 (18.4%) | 32 (31.7%) | 7 (6.3%) |
FDR, false discovery rate; MS, multiple sclerosis; n, number of patients; p, p value.
Shown is the number (percentage) of patients who took none, one or more drugs with potentially harmful effects on the foetus or newborn according to at least one of the four databases used; Significance values <0.05 are indicated in bold.
a
The grouping of patients was based on the use of either birth control pills or vaginal rings as hormonal contraceptives.
Chi
Chi-squared test.
**
FDR <0.001