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. 2022 Aug 16;61(2):506–520. doi: 10.1007/s10528-022-10263-y

Fig. 6.

Fig. 6

RP11-79H23.3/miR-29c promoted cell proliferation and metastasis of NSCLC through Wnt/β-catenin signaling pathway. Cells were transfected with RP11-79H23.3 siRNA, combined with Anti-miR-29c or Anti-miR-29c transfection alone, and the alterations of proliferation, migration, or invasion abilities, as well as the activation of Wnt/β-catenin signaling pathway were determined. A and G CCK8 assay of the alterations of cell proliferation rate in A549 (A) and H1299 (G) cells. B and H Colony formation assay of cell proliferation in A549 (B) and H1299 (H) cells. C and I Wound healing assay of cell migration capability in A549 (C) and H1299 (I) cells. D and J Transwell migration assay of cell migration ability in A549 (D) and H1299 (J) cells. E and K Transwell invasion assay of cell invasion capability in A549 (E) and H1299 (K) cells. F and L Western blot analysis of the activation of Wnt/β-catenin signaling pathway in A549 (F) and H1299 (L) cells. *P < 0.05, **P < 0.01, ***P < 0.001