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. 2023 Mar 16;13(4):1053–1068. doi: 10.1007/s13555-023-00910-6

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 2 — Time to discontinuation based on therapy exposure gap of more than 2× per-label dosing frequency or mode of days of supply for each cohort. CI confidence interval; KM Kaplan–Meier. Notes: (1) Patients at risk of having the event are patients who have not had the event and have not been lost to follow-up at that point in time