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. 2023 Mar 22;17:100487. doi: 10.1016/j.abrep.2023.100487

Table 1.

Respiratory symptom(s), biomarkers of nicotine/tobacco exposure (BOE), sociodemographic characteristics, health conditions, and tobacco-related characteristics of adults who exclusively smoke cigarettes in Waves 1–4 of the PATH Study.

Adults who Exclusively Smoke Cigarettes
Adults who Exclusively Smoke Cigarettes without Respiratory Disease(s)
Weighted M or % 95% CI Weighted M or % 95% CI
Baseline respiratory symptom(s) 55.34 51.98, 58.64 46.51 42.57, 50.49
Follow-up respiratory symptom(s) 52.57 49.99, 55.14 45.54 42.60, 48.52
BOE
 Baseline TNE2 (nmol/mg creau) 0.35 0.33, 0.37 0.32 0.30, 0.34
 Baseline NNAL (pg/mg creau) 2.36 2.24, 2.48 2.22 2.09, 2.38
 Baseline NNN (pg/mg creau) 0.11 0.10, 0.11 0.10 0.10, 0.11
 Baseline CEMA (ng/mg creau) 2.80 2.72, 2.92 2.75 2.61, 2.89
 Baseline CYMA (ng/ml creau) 1.36 1.31, 1.43 1.31 1.23, 1.38
 Baseline Cadmium (pg/mg creau) 2.69 2.55, 2.82 2.45 2.33, 2.58
 Baseline Lead (pg/mg creau) 4.47 4.34, 4.56 4.38 4.25, 4.56
 Follow-up TNE2 (nmol/mg creau) 0.27 0.25, 0.29 0.25 0.23, 0.28
 Follow-up NNAL (pg/mg creau) 2.03 1.91, 2.16 1.91 1.78, 2.05
 Follow-up NNN (pg/mg creau) 0.09 0.09, 0.10 0.09 0.08, 0.10
 Follow-up CEMA (ng/mg creau) 2.69 2.61, 2.80 2.64 2.53, 2.75
 Follow-up CYMA (ng/ml creau) 1.15 1.08, 1.22 1.09 1.02, 1.17
 Follow-up Cadmium (pg/mg creau) 2.85 2.69, 3.00 2.63 2.48, 2.77
 Follow-up Lead (pg/mg creau) 4.30 4.17, 4.43 4.25 4.09, 4.38
Sociodemographics
Age (years) 41.76 41.05, 42.48 40.78 39.97, 41.59
Sex
 Male 44.97 42.44, 47.53 47.82 44.86, 50.81
 Female 55.03 52.47, 57.56 52.18 49.19, 55.14
Race
 White 79.46 77.43, 81.25 79.04 76.60, 82.30
 Black 14.10 12.37, 16.02 15.08 12.97, 17.47
 Asian 1.55 1.15, 2.10 1.73 1.24, 2.42
 Other (includes 2 + races) 4.89 4.24, 5.64 4.14 3.53, 4.84
Ethnicity
 Non-Hispanic 89.46 88.01, 90.76 90.95 89.88, 91.91
 Hispanic 10.54 9.24, 11.99 9.05 8.09, 10.12
Educational attainment
 Less than high school, some high school (no diploma), or GED 25.29 23.30, 27.40 24.84 22.61, 27.22
 High school graduate-diploma 29.53 27.15, 32.03 30.12 27.35, 33.03
 Some college (no degree) or associate degree 35.21 32.67, 37.84 33.93 30.96, 37.04
 Bachelor's degree 8.09 7.16, 9.14 9.16 8.02, 10.44
 Advanced degree 1.87 1.49, 2.34 1.95 1.50, 2.53
Health Conditions
Diagnosed respiratory disease(s) 24.37 22.27, 26.60
 Asthma 14.24 12.41, 16.29
 COPD 6.75 5.60, 8.10
 Emphysema 3.84 2.84, 5.17
 Chronic bronchitis 8.13 6.85, 9.63
 Other 4.16 3.44, 5.03
Tobacco-related Characteristics
Secondhand smoke exposure 61.86 59.39, 64.27 59.85 56.94, 62.70
Household rule on use of combustible tobacco products
 Not allowed 54.74 52.16, 57.30 57.54 54.52, 60.49
 Allowed in some places 26.37 24.01, 28.87 25.05 22.34, 27.97
 Allowed in all places 18.89 17.14, 20.77 17.41 15.43, 19.59
Pack years 19.33 18.07, 20.59 16.40 15.40, 17.40
P30D cannabis use 18.01 16.98, 19.03 24.35 21.61, 27.33
Cigarettes per month (30D) 456.39 402.87, 509.92 416.55 396.22, 436.87
P30D menthol cigarette use 38.47 36.02, 40.99 40.93 37.99, 43.93

M = Geometric mean; CI = confidence interval; P30D = past 30 day; COPD = chronic obstructive pulmonary disease; Creau = creatinine. Notes: Geometric means and percentages are based on weighted data using Wave 4 “all-waves” urine weights; All BOEs were creatinine-standardized and natural log-transformed prior to analysis.