Table 3.
Comparison of anthropometric and hormonal data between girls of group PA+/AT+ and those of groups PA−/AT−, PA−/AT+ and PA+/AT−.
| Variable | Group PA+/AT + vs. Group PA−/AT− | Group PA+/AT + vs. Group PA−/AT+ | Group PA+/AT + vs. Group PA+/AT− |
|---|---|---|---|
| P value | |||
| BMI | 0.012 | 0.279 | 0.261 |
| Leptin | 0.026* | 0.788 | 0.542 |
| TSH | 0.016 | 0.955 | 0.043 |
| FT4 | 0.056 | 0.529 | 0.082 |
Group PA−/AT+, girls with autoimmune thyroiditis (AT) but no premature adrenarche (PA); Group PA+/AT−, girls with PA but no AT; Group PA+/AT+, girls with PA and AT; Group PA−/AT−, girls without PA or AT (controls).
Vs: vs.; BMI: body mass index; TSH: thyroid-stimulating hormone; FT4: free thyroxine.
We used linear regression to investigate whether leptin levels differed among the four groups when adjusting for the effect of BMI. Group PA+/AT+ did not differ significantly from any other group, when adjusting for BMI. The only statistically significant difference after adjusting for BMI was observed between Groups PA−/AT+ and PA−/AT− (p = 0.048). All other pairwise comparisons were not statistically significant.