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. 2023 Mar 16;17:1105530. doi: 10.3389/fnins.2023.1105530

FIGURE 1.

FIGURE 1

CXCL12-GFP and eGFP were upregulated in the lumbar enlargement of the spinal cord. (A) Adeno-associated virus (AAV)-mediated upregulation of CXCL12 and eGFP in the lumbar enlargement was robust. On the 21st day after infection, immunofluorescence showed that the level of CXCL12 in the lumbar enlargement was much higher in the CXCL12-GFP group than in the eGFP group, and the CXCL12 and eGFP signals in the white matter were stronger than those in the gray matter of the spinal cord. The bar in the lower right represents 50 μm. (B) Western blot (WB) results also show that the expression of CXCL12 in spinal cord of CXCL12 group, particularly in regions surrounding the cannula tip, was higher than the eGFP group.