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Differentiation of oligodendrocyte precursor cells (OPCs) into oligodendrocytes in vitro requires the induction of CXCL12. In vitro, 10 ng/ml CXCL12 promoted the differentiation of OPCs. Moreover, 400 ng/ml AMD3100 combined with CXCL12 inhibited differentiation. The bar in the lower right represents 50 μm.
