Table 4.
Association between glycolipid biomarkers and OSA risk after excluding participants with COPD and CVDs.
| Sample size | Adjusted OR (95% CI)* | ||||
|---|---|---|---|---|---|
| Non-OSA | Pre-OSA | OSA | Pre-OSA vs. Non-OSA | OSA vs. Non-OSA | |
| HDL-CH | |||||
| Quartile 1 (≤ 1.21) | 1748 | 461 | 284 | 1.00 | 1.00 |
| Quartile 2 (> 1.21 ~ ≤ 1.46) | 1812 | 372 | 206 | 0.89 (0.74, 1.07) | 0.81 (0.63, 1.04) |
| Quartile 3 (> 1.46 ~ ≤ 1.76) | 1946 | 345 | 153 | 0.92 (0.76, 1.11) | 0.70 (0.53, 0.92) |
| Quartile 4 (> 1.76) | 2010 | 273 | 123 | 0.76 (0.62, 0.93) | 0.57 (0.42, 0.76) |
| P for trend | 0.014 | <0.001 | |||
| Every 1 mmol/l increment | 0.82 (0.69, 0.96) | 0.61 (0.47, 0.78) | |||
| LDL-CH | |||||
| Quartile 1 (≤ 2.95) | 1904 | 343 | 170 | 1.00 | 1.00 |
| Quartile 2 (> 2.95 ~ ≤ 3.56) | 1905 | 357 | 190 | 1.12 (0.92, 1.36) | 1.14 (0.85, 1.53) |
| Quartile 3 (> 3.56 ~ ≤ 4.24) | 1873 | 370 | 205 | 1.12 (0.88, 1.43) | 1.07 (0.76, 1.50) |
| Quartile 4 (> 4.24) | 1834 | 381 | 201 | 1.10 (0.87, 1.40) | 0.93 (0.66, 1.30) |
| P for trend | NA | 0.529 | 0.501 | ||
| Every1 mmol/l increment | 1.00 (0.92, 1.09) | 0.98 (0.88, 1.1) | |||
| Cholesterol | |||||
| Quartile 1 (> 4.72) | 1877 | 365 | 163 | 1.00 | 1.00 |
| Quartile 2 (> 4.72 ~ ≤ 5.39) | 1888 | 348 | 208 | 0.89 (0.72, 1.09) | 1.01 (0.75, 1.37) |
| Quartile 3 (> 5.39 ~ ≤ 6.12) | 1909 | 367 | 183 | 0.93 (0.72, 1.19) | 0.79 (0.56, 1.14) |
| Quartile 4 (> 6.12) | 1842 | 371 | 212 | 0.87 (0.68, 1.12) | 0.83 (0.58, 1.18) |
| P for trend | 0.387 | 0.184 | |||
| Every 1 mmol/l increment | 0.96 (0.89, 1.03) | 0.95 (0.86, 1.06) | |||
| Triglyceride | |||||
| Quartile 1 (≤ 0.95) | 2029 | 293 | 130 | 1.00 | 1.00 |
| Quartile 2 (> 0.95 ~ ≤ 1.34) | 1933 | 337 | 157 | 1.09 (0.89, 1.34) | 1.02 (0.75, 1.40) |
| Quartile 3 (> 1.34 ~ ≤ 1.95) | 1829 | 378 | 222 | 1.29 (1.05, 1.58) | 1.58 (1.17, 2.14) |
| Quartile 4 (> 1.95) | 1725 | 443 | 257 | 1.32 (1.07, 1.63) | 1.42 (1.04, 1.94) |
| P for trend | 0.003 | 0.003 | |||
| Every 1 mmol/l increment | 1.00 (0.96, 1.05) | 1.03 (0.98, 1.09) | |||
| Fasting blood glucose (FBG) | |||||
| Q1 (≤ 4.84) | 2061 | 296 | 146 | 1.00 | 1.00 |
| Q2 (> 4.84 ~ ≤ 5.18) | 1904 | 324 | 151 | 1.08 (0.89, 1.32) | 0.98 (0.72, 1.33) |
| Q3 (> 5.18 ~ ≤ 5.68) | 1849 | 396 | 215 | 1.15 (0.95, 1.40) | 1.14 (0.86, 1.52) |
| Q4 (> 5.68) | 1702 | 435 | 254 | 1.34 (1.08, 1.66) | 1.31 (0.96, 1.78) |
| P for trend | 0.006 | 0.054 | |||
| Every 1 mmol/L increment | 1.04 (0.98, 1.11) | 1.03 (0.95, 1.11) | |||
*
Adjustment for age, gender, marital status, educational status, body mass index, leisure-time physical activity, waist-hip ratio, PM2.5 concentration, work intensity, active smoking, passive smoke, alcohol drinking, fruit intake, fresh vegetable intake, hypertension, dyslipidemia, diabetes, chronic obstructive pulmonary disease, and cardiovascular diseases.
HDL-CH, high-density lipoprotein cholesterol; LDC-CH, low-density lipoprotein cholesterol; OSA, obstructive sleep apnea; FBG, obstructive sleep apnea; CVDs, cardiovascular diseases; COPD, chronic obstructive pulmonary disease.