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. 2023 Mar 16;14:1115890. doi: 10.3389/fendo.2023.1115890

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Copyright © 2023 Zhang, Shen, Chen, Jiang, Yuan, Xie, Zhang and Xu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional enrichment of MergeCohort_Turquoise and GSE135251_Turquoise module. (A) Venn diagram displays number of genes overlapped between MergeCohort_Turquoise and GSE135251_Turquoise module. (B) Spearman’s correlation between the kWithin of common genes (n = 289) overlapped between each module. Top 25 hub genes with the highest kWithin from MergeCohort_Turquoise module are shown. (C) Dot-plot heatmap shows top 20 significantly enriched disease by genes in each module. The size of each dot represent the gene counts enriched in each disease term. (D) Dot-plot heatmap shows top 20 significantly enriched KEGG pathways by genes in each module. The size of each dot represents the -log₁₀ of p value for each KEGG pathway term.