Table. Patient Characteristics.
| Characteristic | Patients, No. (%) | |||
|---|---|---|---|---|
| Total | Treatment | |||
| WW | LE | TME | ||
| No. (%) | 278 (100) | 221 (79.5) | 18 (6.5) | 39 (14.0) |
| Age, median (range), y | 66 (34-85) | 66 (44-85) | 67 (48-85) | 62 (34-83) |
| <60 | 77 (27.7) | 59 (26.7) | 5 (27.8) | 13 (33.3) |
| 60-69 | 103 (37.1) | 81 (36.7) | 7 (38.9) | 15 (38.5) |
| ≥70 | 98 (35.3) | 81 (36.7) | 6 (33.3) | 11 (28.2) |
| Sex | ||||
| Male | 187 (67.3) | 151 (68.3) | 11 (61.1) | 25 (64.1) |
| Female | 91 (32.7) | 70 (31.7) | 7 (38.9) | 14 (35.9) |
| Clinical T stage | ||||
| cT1-2 | 55 (19.8) | 48 (21.7) | 3 (16.7) | 4 (10.3) |
| cT3 | 202 (72.7) | 157 (71.0) | 14 (77.8) | 31 (79.5) |
| cT4 | 21 (7.6) | 16 (7.2) | 1 (5.6) | 4 (10.3) |
| Clinical N stage | ||||
| cN0 | 72 (25.9) | 56 (25.3) | 4 (22.2) | 12 (30.8) |
| cN1 | 92 (33.1) | 70 (31.7) | 8 (44.4) | 16 (41.0) |
| cN2 | 114 (41.0) | 95 (43.0) | 6 (33.3) | 14 (35.9) |
| Tumor distance from anorectal junction, median (range), cm | 3.0 (0-15) | 3.0 (0-15) | 2.5 (0-10) | 3.5 (0-13) |
| <5 | 164 (59.0) | 133 (60.2) | 12 (66.7) | 19 (48.7) |
| ≥5 | 114 (41.0) | 88 (39.8) | 6 (33.3) | 20 (51.3) |
| Neoadjuvant treatment | ||||
| Short course of radiotherapy | 15 (5.4) | 8 (3.6) | 4 (22.2) | 3 (7.7) |
| Chemoradiotherapy | 263 (94.6) | 213 (96.4) | 14 (77.8) | 36 (92.3) |
| Responsea | ||||
| Clinical complete response | 153 (55.0) | 131 (59.3) | 6 (33.3) | 16 (41.0) |
| Clinical near-complete response | 125 (45.0) | 90 (40.7) | 12 (66.7) | 23 (59.0) |
| Colostomyb | ||||
| No | 242 (87.1) | 221 (100) | 18 (100) | 3 (7.7) |
| Yes | 36 (12.9) | 0 | 0 | 36 (92.3) |
Abbreviations: LE, local excision; TME, total mesorectal excision; WW, patients followed up by a watch-and-wait approach without requiring additional surgery.
a
Clinical response at restaging 8 to 12 weeks after chemoradiotherapy or radiotherapy.
b
Patients with or without a colostomy at 24 months.