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. 2022 Dec 8;16(4):711–721. doi: 10.1093/ckj/sfac262

Figure 3:

Figure 3:

Predictive value of urinary QA/3-OH AA for AKI development. (A) Low quantile and high quantile are determined by the median of urinary QA/3-OH AA (5.51) in MTX cohort. In unadjusted model, the upper quantile of urinary QA/3-OH AA has 4.27 (95% confidence interval 1.67 to 10.69) odds for the development of AKI after HDMTX. After adjusting for age, sex and diabetes, the odds ratio is 3.25 (95% confidence interval 1.19 to 8.93). (B) ROC curves show the predictive performance for AKI after HDMTX. AUC for urinary QA/3-OH AA is 0.749(SEM 0.044). The clinical model is comprised of age, sex and diabetes and AUC for the clinical model is 0.672 (SEM 0.052). AUC for the combination of clinical model and urinary QA/3-OH AA is 0.772 (SEM 0.041). (C) ROC curves show the predictive performance for AKI after liver transplantation. AUC for urinary QA/3-OH AA is 0.729 (SEM 0.079).