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. Author manuscript; available in PMC: 2023 Mar 30.
Published in final edited form as: Connect Tissue Res. 2021 Jan 25;63(1):69–81. doi: 10.1080/03008207.2020.1871475

Figure 2. Effects of dynamic hydrostatic pressure on DNA and S-GAG content in chondrocyte-seeded agarose constructs.

Figure 2.

(a) DNA content of tissue engineered cartilage was unchanged by dynamic hydrostatic pressure, while (b) S-GAG content of tissue engineered cartilage and (c) S-GAG content normalized to DNA content were significantly reduced by hydrostatic pressure in a frequency and magnitude-dependent manner. (d) Amount of S-GAG release into the media as a function of culture duration (e) S-GAG retention fraction (f) Total S-GAG content synthesis. Groups not sharing a letter indicate statistically significant differences. n=5–6 per group. Groups with (*) are significantly different from the control (0 MPa).