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. 2023 Mar 9;11(5):203. doi: 10.21037/atm-22-4357

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2023 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Time course of respiratory mechanics. (A) PaO₂/FiO₂. (B) Time course of FiO₂. (C) Driving pressure. (D) Cdyn. *P<0.05; **P<0.01. Group C, control group with a fixed PEEP of 5 cmH₂O; group O, optimized PEEP group with an individualized PEEP at which SpO₂ was maintained at 95–96% with minimal FiO₂; PEEP, positive end-expiratory pressure; PaO₂, partial pressure of oxygen in arterial blood; FiO₂, fraction of inspired oxygen; Cdyn, dynamic compliance.