Comparison 34. Any mechanical method and low dose misoprostol versus prostaglandin E2 alone: all women.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
34.1 Vaginal delivery not achieved in 24 hours	1	350	Risk Ratio (M‐H, Fixed, 95% CI)	1.14 [0.89, 1.46]
34.2 Uterine hyperstimulation with FHR changes	1	327	Risk Ratio (M‐H, Fixed, 95% CI)	0.75 [0.27, 2.13]
34.3 Caesarean section	1	350	Risk Ratio (M‐H, Fixed, 95% CI)	0.85 [0.57, 1.25]
34.4 Serious neonatal morbidity/perinatal death	1	345	Risk Ratio (M‐H, Fixed, 95% CI)	2.04 [0.19, 22.24]
34.5 Serious maternal morbidity or death	1	0	Risk Ratio (M‐H, Fixed, 95% CI)	Not estimable
34.6 Oxytocin augmentation	1	350	Risk Ratio (M‐H, Fixed, 95% CI)	0.54 [0.34, 0.86]
34.7 Uterine hyperstimulation without fetal heart rate changes	1	327	Risk Ratio (M‐H, Fixed, 95% CI)	0.54 [0.22, 1.32]
34.8 Uterine rupture	1	0	Risk Ratio (M‐H, Fixed, 95% CI)	Not estimable
34.9 Instrumental vaginal delivery	1	350	Risk Ratio (M‐H, Fixed, 95% CI)	1.01 [0.26, 3.98]
34.10 Meconium‐stained liquor	1	339	Risk Ratio (M‐H, Fixed, 95% CI)	1.15 [0.60, 2.23]
34.11 Apgar score < 7 at 5 minutes	1	346	Risk Ratio (M‐H, Fixed, 95% CI)	0.68 [0.25, 1.88]
34.12 Neonatal intensive care unit admission	1	346	Risk Ratio (M‐H, Fixed, 95% CI)	0.68 [0.12, 4.03]
34.13 Perinatal death	1	345	Risk Ratio (M‐H, Fixed, 95% CI)	1.02 [0.06, 16.14]
34.14 Maternal side effects	1	314	Risk Ratio (M‐H, Fixed, 95% CI)	1.16 [0.95, 1.43]
34.15 Maternal nausea	1	300	Risk Ratio (M‐H, Fixed, 95% CI)	1.65 [0.98, 2.79]
34.16 Maternal diarrhoea	1	313	Risk Ratio (M‐H, Fixed, 95% CI)	3.72 [1.53, 9.00]
34.17 Postpartum haemorrhage	1	348	Risk Ratio (M‐H, Fixed, 95% CI)	0.98 [0.67, 1.41]
34.18 Serious maternal complications	1	0	Risk Ratio (M‐H, Fixed, 95% CI)	Not estimable
34.19 Maternal fever during labour	1	347	Risk Ratio (M‐H, Fixed, 95% CI)	1.53 [0.26, 9.02]