Table 3.

Hazard Ratios of Incident Dementia (With 95% CI) for Participants With Weak Social Networks (LSNS score ≤ 29), Computed by Cox Proportional Hazards Models for the First 10 Years of Follow-Up

Model	N	Baseline Covariates	Hazard Ratio (95% Confidence Interval) and p Value
			All-Cause Dementia (N = 173)	p Value	Alzheimer’s Disease (N = 104)	p Value	Vascular Dementia (N = 38)	p Value
1	2636	None (unadjusted)	1.85 (1.36–2.52)	<.001	2.01 (1.34–3.01)	<.001	1.78 (0.920–3.45)	.086
2	2583	Age, education, APOE ɛ4, and prevalent stroke	1.64 (1.20–2.24)	.002	1.79 (1.19–2.70)	.005	1.50 (0.77–2.93)	.238
3	2578	Age, education, APOE ɛ4, prevalent stroke, depressive symptoms, and CASI score	1.52 (1.11–2.08)	.009	1.67 (1.11–2.51)	.014	1.34 (0.68–2.64)	.392

Notes: The group with strong social networks is used as a reference. Results are shown for unadjusted models and with adjustment for baseline covariates (age, education, APOE ɛ4 status, prevalent stroke, and depressive symptoms [CES-D score ≥ 9]), as indicated. p Values shown in bold indicate associations that are significant after Bonferroni correction for multiple comparisons. LSNS = Lubben Social Network Scale; CES-D Scale = Center for Epidemiologic Studies Depression (CES-D) 11-item Scale; CASI = Cognitive Abilities Screening Instrument.