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. 2023 Mar 10;5(10):223–228. doi: 10.46234/ccdcw2023.041

Table 2. Factors associated with hesitancy to receive the first and second booster doses of the COVID-19 vaccine (N=525).

Characteristic Hesitancy to receive the
third dose of COVID-19 vaccine
Hesitancy to receive the
fourth dose of COVID-19 vaccine
OR (95% CI) P value AOR*
(95% CI)
P value OR (95% CI) P value AOR*
(95% CI)
P value
Abbreviation: OR=crude odds ratio; AOR=adjusted odds ratio; CI=confidence interval; NA=not applicable.
* Adjusted for significant background characteristics listed in Supplementary Table S2.
Individual-level variables
Positive attitude scale 0.83
(0.76, 0.92)
<0.001 0.83
(0.76, 0.92)
<0.001 0.65
(0.60, 0.74)
<0.001 0.66
(0.60, 0.74)
<0.001
Negative attitude scale 1.01
(0.97, 1.06)
0.553 1.01
(0.97, 1.06)
0.560 1.03
(0.99, 1.08)
0.147 1.03
(0.99, 1.08)
0.195
Perceived subjective norms 0.54
(0.43, 0.67)
<0.001 0.55
(0.44, 0.69)
<0.001 0.39
(0.30, 0.49)
<0.001 0.40
(0.31, 0.51)
<0.001
Perceived behavioral control 0.54
(0.43, 0.67)
<0.001 0.51
(0.40, 0.63)
<0.001 0.25
(0.19, 0.34)
<0.001 0.25
(0.19, 0.34)
<0.001
Vaccination fatigue (tired of receiving COVID-19 vaccination over and over again) 1.34
(1.18, 1.58)
<0.001 1.36
(1.18, 1.58)
<0.001 1.48
(1.28, 1.71)
<0.001 1.52
(1.31, 1.78)
<0.001
Hesitancy to receive the third dose of COVID-19 vaccine NA NA NA NA 14.05
(7.94, 24.79)
<0.001 14.05
(8.05, 24.52)
<0.001
Interpersonal variables
Media exposure scale 0.93
(0.89, 0.99)
0.012 0.94
(0.89, 0.99)
0.033 0.90
(0.85, 0.95)
<0.001 0.90
(0.85, 0.95)
<0.001
Frequency of thoughtful consideration about veracity of COVID-19-specific information 0.64
(0.53, 0.77)
<0.001 0.65
(0.54, 0.79)
<0.001 0.51
(0.42, 0.62)
<0.001 0.52
(0.43, 0.64)
<0.001