FIG 3.

Age-dependent mortality rates for BALB/c mice infected i.c. with SADS-CoV. BALB/c mice of different ages were inoculated i.c. with SADS-CoV or cell culture medium and observed daily. (A to C) Survival (A), clinical scores (B), and body weight changes (C) of 7-day-old mice. (D to F) Survival (D), clinical scores (E), and body weight changes (F) of 14-day-old mice. (G to I) Survival (G), clinical scores (H), and body weight changes (I) of 21-day-old mice. (J to L) Survival (J), clinical scores (K), and body weight changes (L) of 42-day-old mice. (M) Intestinal samples from SADS-CoV-infected and mock-infected 7-day-old mice. (N) SADS-CoV genome copy numbers in different tissues, as determined by real-time PCR analysis.