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MRL/lpr mice were hypermetabolic. Comprehensive laboratory animal monitoring system (CLAMS) was performed at age of 14 weeks. VO2 (A), CO2 (B), heat production (D), activity (E), and food consumption (F) were measured, and respiratory exchange ratio (C) was calculated. n=4. *p<0.05, ***p<0.001, ****p<0.0001 vs MRL (control). ns, not significant.
