Table 3.
Breakdown of endpoints
| Endpoint description | AVATAR arm | Anti-arrhythmic arm | Conventional arm | |||
|---|---|---|---|---|---|---|
| n = 110 | n = 103 | n = 108 | ||||
| Primary endpoints | 23 (20.9%) | 76 (73.8%) | 19 (17.6%) | |||
| Primary endpoint timing | Failed 12-week discharge | After 12 weeks | Failed 12-week discharge | After 12 weeks | Failed 12-week discharge | After 12 weeks |
| 9 (8.2%) | 14 (12.7%) | 36 (35.0%) | 40 (38.8%) | 6 (5.6%) | 13 (12.0%) | |
| ER visit leading to inpatient admission | 1 (0.9%) | 3 (2.9%) | 4 (3.7%) | |||
| ER visit leading to discharge | 2 (1.8%) | 4 (3.9%) | 1 (0.9%) | |||
| Outpatient consultation | 20 (18.2%) | 69 (67.0%) | 14 (13.0%) | |||
| Symptoms of atrial arrhythmia with ECG documentation at primary endpoint | 16 (14.5%) | 25 (24.3%) | 9 (8.3%) | |||
| Symptoms of atrial arrhythmia without ECG documentation at primary endpoint | 7 (6.4%) | 43 (41.7%) | 10 (9.3%) | |||
| Treatment complication/drug side effects at primary endpoint | 0 | 8 (7.8%) | 0 | |||
| Ablation after primary endpoint | 9 (8.2%) | 53 (51.5%) | 15 (13.9%) | |||
| Medication alteration after primary endpoint | 4 (3.6%) | 6 (5.8%) | 2 (1.9%) | |||
| Investigations only after primary endpoint | 7 (6.4%) | 16 (15.5%) | 1 (0.9%) | |||
| No action after primary endpoint | 3 (2.7%) | 1 (1.0%) | 1 (0.9%) | |||
AVATAR, Ablation Versus Anti-arrhythmic Therapy for Reducing All Hospital Episodes from Recurrent.