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. 2023 Feb 9;25(3):1041–1050. doi: 10.1093/europace/euad016

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© The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Two-year combined device-related chronic complication and select reinterventions. Notes: hazards ratios of 2-year combined device-related chronic complications (device breakdown, dislodgment, other mechanical complications, infection, device-related pain, device-related stenosis, and pocket complications) and select reinterventions (system revision, lead revision or replacement, system replacement, system removal) rates between leadless-VVI patients and transvenous-VVI patients for each high-risk subgroup, estimated with Fine–Gray competing risk models. Spikes represent Bonferroni-adjusted confidence intervals (number of tests = 27). aDCSI, adapted Diabetes Complication Severity Index; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; ESRD, end-stage renal disease. ESRD and CKD Stages 4 or 5 are not mutually exclusive.