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. 2023 Feb 9;25(3):1041–1050. doi: 10.1093/europace/euad016

Table 4.

Mortality rates at 30 days and 2 years

30-day mortality 2-year mortality
L-VVI rate (%) TV-VVI rate (%) Unadjusted OR
(confidence interval)
Adjusted OR
(confidence interval)
L-VVI rate (%) TV-VVI rate (%) Unadjusted HR
(confidence interval)
Adjusted HR
(confidence interval)
COPD 5.84 5.69 1.031
(0.795–1.339)
0.928
(0.710–1.215)
42.53 40.64 1.110
(1.003–1.229)
1.048
(0.944–1.164)
Diabetes 4.72 4.50 1.053
(0.816–1.358)
0.871
(0.671–1.131)
37.05 33.57 1.175
(1.072–1.288)
1.041
(0.946–1.146)
ȃDiabetes with high aDCSI 5.92 5.84 1.013
(0.751–1.365)
0.901
(0.661–1.228)
44.46 40.93 1.147
(1.031–1.277)
1.049
(0.936–1.175)
ESRD or CKD Stages 4 and 5 8.48 8.34 1.016
(0.714–1.447)
1.003
(0.688–1.462)
54.41 54.73 1.018
(0.893–1.161)
1.004
(0.873–1.155)
ȃESRD 8.48 11.37 0.722
(0.451–1.156)
0.802
(0.491–1.309)
57.56 60.98 0.913
(0.765–1.090)
0.978
(0.814–1.175)
ȃCKD Stages 4 and 5 8.77 7.48 1.199
(0.813–1.768)
1.138
(0.754–1.719)
55.12 53.47 1.090
(0.934–1.272)
1.039
(0.882–1.225)
Malignancy 4.97 4.22 1.205
(0.902–1.608)
1.033
(0.770–1.386)
34.95 33.15 1.116
(1.003–1.242)
1.023
(0.916–1.143)
ȃMalignancy without treatment 4.32 3.97 1.098
(0.782–1.543)
0.975
(0.691–1.375)
31.85 31.16 1.072
(0.950–1.209)
1.010
(0.892–1.142)
Tricuspid valve disease 4.73 4.12 1.150
(0.841–1.573)
1.024
(0.745–1.408)
34.66 32.87 1.113
(1.000–1.24)
1.044
(0.935–1.167)

Hazard ratios and odds ratios adjusted using overlapping weights. Confidence Intervals adjusted for multiple comparisons (number of tests = 9). ESRD and CKD Stages 4 or 5 are not mutually exclusive.

aDCSI, adapted Diabetes Complication Severity Index; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; ESRD, end-stage renal disease; HR, hazard ratio; L-VVI, leadless-VVI; OR, odds ratio; TV-VVI, transvenous-VVI.