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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Nat Microbiol. 2023 Jan 12;8(2):218–230. doi: 10.1038/s41564-022-01301-x

Table 1.

Participant characteristics and symptoms

AR patients Healthy controls (HC) p value1 AR type by frequency AR type by seasonality AR type by severity
Intermittent Persistent p value1 Seasonal Perennial p value1 Mild Moderate-severe p value1
n 55 102 25 30 27 28 26 29
Age 31.38 ± 6.56 32.68 ± 11.73 31.24 ± 7.00 31.50 ± 6.29 32.19 ± 7.10 30.61 ± 6.02 32.81 ± 6.80 30.10 ± 6.17
Sex
male 27 (49%) 63 (62%) 0.13 10 (40%) 17 (57%) 0.28 12 (44%) 15 (54%) 0.59 10 38.5% 12 41.4% >0.9999
female 28 (51%) 39 (38%) 15 (60%) 13 (43%) 15 (56%) 13 (46%) 16 61.5% 17 58.6%
Nasal symptoms
Obstruction 51 (93%) 0 (0%) <0.0001 23 (92%) 28 (93%) >0.9999 25 (93%) 26 (93%) 0.67 22 (85%) 29 (100%) 0.044
Itchiness 46 (84%) 0 (0%) <0.0001 19 (76%) 27 (90%) 0.27 23 (85%) 23 (82%) >0.9999 21 (81%) 25 (86%) 0.72
Sneezing 47 (86%) 0 (0%) <0.0001 21 (84%) 26 (87%) >0.9999 23 (85%) 24 (86%) >0.9999 20 (77%) 27 (93%) 0.13
Clear discharge 49 (89%) 0 (0%) <0.0001 20 (80%) 29 (97%) 0.082 23 (85%) 26 (93%) 0.42 22 (85%) 27 (93%) 0.41
Other symptoms
Chest tightness 3 (5.5%) 0 (0%) 0.042 2 (8.0%) 1 (3.3%) 0.59 1 (3.7%) 2 (7.1%) >0.9999 1 (3.8%) 2 (6.9%) >0.9999
Cough 6 (11%) 0 (0%) 0.0015 1 (4.0%) 5 (17%) 0.2 2 (7.4%) 4 (14%) 0.67 2 (7.7%) 4 (14%) 0.67
Itchy or red eyes 25 (46%) 0 (0%) <0.0001 11 (44%) 14 (47%) >0.9999 8 (30%) 17 (61%) 0.031 9 (35%) 16 (55%) 0.27
Ear occlusion or hearing loss 6 (11%) 0 (0%) 0.0015 1 (4.0%) 5 (17%) 0.2 2 (7.4%) 4 (14%) 0.67 2 (7.7%) 4 (14%) 0.67
1

Fisher’s exact test. Significance (p<0.05) is indicated by bold face of p values.