Table 2.
FBC/reference range | HbSC (mean ± SD) | HbSF (mean ± SD) | HbSS (mean ± SD) | p Values |
---|---|---|---|---|
RBC (2.5−5.50) | 3.878 ± 0.8197 | 2.894 ± 0.5588 | 2.818 ± 1.315 | 0.0001 |
HGB (8.0−17.0) | 9.796 ± 1.296 | 8.856 ± 1.081 | 8.020 ± 1.288 | 0.0001 |
HCT (26.0−50.0) | 27.29 ± 3.717 | 24.40 ± 2.958 | 22.32 ± 3.394 | 0.0001 |
MCV (86−110.0) | 71.96 ± 8.876 | 85.68 ± 10.49 | 86.11 ± 10.84 | 0.0001 |
PLT (50−400) | 299.5 ± 106.6 | 345.4 ± 206.8 | 311.9 ± 154.6 | 0.9960 |
WBC (3.00−15.00) | 9.412 ± 3.463 | 7.199 ± 3.116 | 10.14 ± 3.565 | 0.0467 |
Abbreviations: HCT, hematocrit; HGB, hemoglobin; MCV, mean corpuscular volume; PLT, platelet; RBC, red blood cell; SCD, sickle cell disease; WBC, white blood count.
Mean ± SD values of scavenger protein among variants of SCD compared to their respective reference values.
p Values generated by Kruskal−Wallis test.