Table 1. Adverse Reactions Occurring in ≥ 10% of Patients.

Adverse reactions		All grades, %	Grades 3–4, %
General disorders and administration site conditions	Pyrexia	76	3.0
	Injection site reaction	37	0.6
	Fatigue	33	2.4
	Chills	16	0
	Pain	15	1.8
	Edema	13	0
Immune system disorders	Cytokine release syndrome	72	0.6
	Hypogammaglobulinemia	11	1.2
Musculoskeletal and connective tissue disorders	Musculoskeletal pain	44	4.2
	Bone pain	16	3.0
Infections	Upper respiratory tract infection	26	2.4
	Pneumonia	24	15.0
	Urinary tract infection	11	5.0
Gastrointestinal disorders	Nausea	25	0.6
	Diarrhea	21	2.4
	Constipation	18	0
	Vomiting	12	0.6
Vascular disorders	Hypotension	18	1.2
	Hemorrhage	12	1.8
	Hypertension	12	4.8
Respiratory, thoracic, and mediastinal disorders	Hypoxia	18	1.8
	Cough	15	0
Cardiac disorders	Cardiac arrhythmia	16	1.8
Metabolism and nutrition disorders	Decreased appetite	11	0.6
Renal and urinary disorders	Acute kidney injury	11	3.6

Note. Information from Janssen Biotech, Inc. (2022).