Table 1.
An overview of reported SynComs in chronological order.
| Yeara | Consortium name | Designb | Number of species | Number of phyla | Names of phyla presentc | Testing system | Reference |
|---|---|---|---|---|---|---|---|
| 2008 | - | TD | 7 | 4 | A, C, F, P | Murine | Martin et al. (2008) |
| 2009 | - | TD | 2 | 2 | B, F | Murine | Mahowald et al. (2009) |
| - | BU | 3 | 3 | A, F, P | Murine | Denou et al. (2009) | |
| - | TD | 2 | 2 | B, P | Murine | Goodman et al. (2009) | |
| 2011 | SIHUMI(x) | TD | 7/8 | 4 | A, B, F, P | Rat | Becker et al. (2011) |
| - | TD | 10 | 4 | A, B, F, P | Murine | Rezzonico et al. (2011) | |
| - | TD | 19 | 3 | A, B, F | Murine | McNulty et al. (2011) | |
| - | BU | 10 | 4 | A, B, F, T | Murine | Faith et al. (2011) | |
| 2013 | Shumix-9 | TD | 9 | 4 5 |
A, B, F, P A, B, F, FU, P |
Murine | Ganesh et al. (2013), Slezak et al. (2013, 2014) |
| Shumix-7 | TD | 7 | 4 | A, B, F, P | Rat | Woting et al. (2014) | |
| - | TD | 23 | 1 | F | Murine | Atarashi et al. (2013) | |
| - | TD | 2 | 2 | B, F | Rat | Wrzosek et al. (2013) | |
| - | TD | 2 | 2 | A, B | Murine | Marcobal et al. (2013) | |
| - | TD | 9 | 4 | A, B, F, P | Murine | Rey et al. (2013) | |
| - | TD | 14 | 2 | A, B, F | Murine | Reyes et al. (2013) | |
| RePOOPulate | BU | 33 | 4 | A,B,F,P | Human | Petrof et al. (2013) | |
| - | BU | 3 | 3 | B, E, F | Murine | (Shoaie et al. (2013) | |
| 2015 | - | TD | 4 | 3 | B, F | Murine | Buffie et al. (2015) |
| MET-2 | BU | 31 | 4 | A, B, F, P, V | Bioreactor | Yen et al. (2015) | |
| 2016 | - | TD | 14 | 5 | A, B, F, V | Murine | Desai et al. (2016) |
| MET-1 | BU | 33 | 5 | A, B, F, P, V | Murine, organoid | Martz et al. (2017), Munoz et al. (2016), Carlucci et al. (2019) | |
| 2017 | - | BU | 4 | 4 | B, F, P | Bioreactor | Pinto et al. (2017) |
| 2018 | - | BU | 12 | 4 | A, B, F, P | Microplate | Venturelli et al. (2018) |
| - | BU | 3 | 1 | F | Bioreactor | D'hoe et al. (2018) | |
| 2019 | SIHUMIx (8) | TD | 8 | 5 | A, B, F, P | Murine | Ring et al. (2019) |
| Simplified intestinal microbiota | TD | 10 | 4 | A, B, P, V | Murine | Kovatcheva-Datchary et al. (2019) | |
| 6-member clostridial consortium | BU | 6 | 1 | F | Murine | Abdel-Gadir et al. (2019) | |
| - | BU | 11 | 4 | B, F, FU | Murine | Tanoue et al. (2019) | |
| - | TD | 14 | 4 | A, B, F, P | Bioreactor | Gutiérrez and Garrido (2019) | |
| - | TD | 20 | 3 | A, B, F, P | Murine | Patnode et al. (2019) | |
| 2021 | - | BU | 25 | 4 | A, B, F, P | Microplate | Clark et al. (2021) |
| GUT-103, GUT-108 | BU | 17 11 |
4 5 |
B, F, V | Murine | van der Lelie et al. (2021) | |
| - | TD | 104 | 5 | A, B, F, P, V | Microplate | Cheng et al. (2021) | |
| MCC100 | TD | 100 | 5 | A, B, E, F, P | Bioreactor | Perez et al. (2021) |
a
Year of the earliest mention of the consortium. bThe design strategy of the SynCom: TD-top-down, BU-bottom-up. cAbbreviations of phyla: A-Actinobacteria, B-Bacteroidetes, E-Euryarchaeota (archaea), F-Firmicutes, FU-Fusobacteria, P-Proteobacteria, T-Thermodesulfobacteriota, and V-Verrucomicrobia.