Table 6.

Toxicity and drug-likeness scores of the compounds 7–12 & 19–36.

Compounds	Drug likeness	Toxicity				Shape Index	Molecular Flexibility	Molecular Complexity
		Mutagenic	Tumorigenic	Reproductive Effective	Irritant
7	3.98	None	High	High	None	0.48	0.31	0.81
8	3.76	None	High	High	None	0.47	0.31	0.82
9	1.99	None	High	High	None	0.47	0.31	0.87
10	3.83	None	High	High	None	0.47	0.31	0.87
11	3.78	None	High	High	None	0.47	0.31	0.85
12	3.83	None	High	High	None	0.47	0.33	0.86
19	1.74	None	None	None	None	0.52	0.48	0.32
20	1.48	None	None	None	None	0.52	0.45	0.33
21	1.55	None	None	None	None	0.52	0.5	0.33
22	−0.32	None	None	None	None	0.52	0.5	0.33
23	1.47	None	None	None	None	0.52	0.5	0.33
24	1.56	None	None	None	None	0.52	0.54	0.36
25	−0.69	None	None	None	None	0.52	0.35	0.81
26	−0.91	None	None	None	None	0.52	0.35	0.82
27	−0.85	None	None	None	None	0.52	0.35	0.88
28	−2.69	None	None	None	None	0.52	0.35	0.88
29	−0.90	None	None	None	None	0.52	0.35	0.84
30	−0.84	None	None	None	None	0.52	0.36	0.85
31	2.35	None	None	None	None	0.53	0.35	0.85
32	2.12	None	None	None	None	0.51	0.35	0.86
33	2.08	None	None	None	None	0.51	0.35	0.88
34	0.29	None	None	None	None	0.51	0.35	0.88
35	2.08	None	None	None	None	0.51	0.35	0.88
36	2.18	None	None	None	None	0.51	0.36	0.89
INH	−5.78	High	High	High	High	0.7	0.48	0.55
PZA	−0.68	High	High	High	None	0.67	0.04	0.72