Table 2. Rabbit infectivity test results.
| Infecting strain | RIT day | Donor Rabbit1 | Time to positive orchitis/DFM2 | Month 1 serology (day 30 post-RIT) | Month 2 serology (day 60 post-RIT) | Month 3 serology (day 90 post-RIT) | |||
|---|---|---|---|---|---|---|---|---|---|
| VDRL3 | TPPA4 | VDRL3 | TPPA4 | VDRL3 | TPPA4 | ||||
| SS14-WT | Day 44 post-IDI | 505 | 74 days | NR | NR | NP | NP | ||
| 512 | 33 days | NP | NP | ||||||
| Day 79 post-IDI | 510 | 35 days | R; 1:20 | R; 1:1280 | |||||
| 511 | 35 days | R; 1:4 | R; 1:80 | ||||||
| SS14-DC KO | Day 44 post-IDI | 507 | N/A | NR | NR | NR | NR | NR | NR |
| 503 | N/A | NR | NR | NR | NR | NR | NR | ||
| Day 79 post-IDI | 501 | N/A | NR | NR | NR | NR | NR | NR | |
| 504 | N/A | NR | NR | NR | NR | NR | NR | ||
1Identification number of ID-infected donor rabbit. Naïve RIT rabbits received lymph-node from the donor rabbits.
2In rabbits with orchitis, treponemes were also detected in testicular needle aspirates using DFM.
3VDRL results (NR = Non-reactive; R = Reactive) and titers are shown. NP: Not performed
4TPPA results (NR = Non-reactive; R = Reactive) and titers are shown when measured. NP: Not performed.