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. 2023 Feb 21;147(14):1097–1109. doi: 10.1161/CIRCULATIONAHA.122.062349

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© 2023 The Authors.

Circulation is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDerivs License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.

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Figure 2. — Forest plots showing the odds ratios of lead variants for genome-wide and nearly genome-wide association loci for PA risk in each cohort. Forest plots for the odds ratios (ORs) of rs3790604 (A), rs2023843 (B), rs145725189 (C), rs4980379 (D), rs35486 (E), and rs35442752 (F) on the risk of primary aldosteronism (PA). Each forest plot shows the estimated ORs and 95% CIs from the cohort-specific genome-wide association study results. The variant name, chromosome position, and risk alleles and nonrisk alleles are shown above each plot. The size of the square representing the OR is proportional to the effective sample size of each cohort. RAF indicates risk allele frequency; and UKB, UK Biobank.