Figure 3. Changes in dynamical stability underlie differences in whole-brain functional connectivity (FC) between controls and patients diagnosed with neurodegenerative diseases.

(A) Distribution of parameters Δ (which encode the contribution of each resting state networks (RSN) towards the local bifurcation parameter) across 300 runs of parameter optimization for CNT, Alzheimer’s disease (AD-), AD+, and behavioral variant frontotemporal dementia (bvFTD) (* indicates $\left|\mathrm{d}\right|$ > 0.8 between distributions). (B) Brain regions with values $\left|\mathrm{d}\right|$ > 0.8 between the local distribution of bifurcation parameters of CNT vs. AD-, AD+, and bvFTD.