Table 1.
Summary of cases.
| Case yr | Demographic | Valve | Antibiotics | Cardiothoracicsurgery | Follow up |
|---|---|---|---|---|---|
| 1 1999 |
46 M IVDU |
TV | 1.MER + GEN 2. MER |
No | Alive > 1 yr |
| 2 2002 |
73M | MV, AV, PPM | 1. TIM + TOB 2. MER |
Yes AVR, MVR, TV repair, removal of PPM lead |
Died 6 mo after Dx from sepsis with other organism |
| 3 2003 |
46 M | MV | 1.TIM + GEN 2.CIP + TOB 3.CAZ + CIP |
No | Clinical cure Alive > 5 yr |
| 4 2003 |
49 M IVDU |
TV | 1. TIM + TOB | Yes TV repair and vegectomy |
Clinical cure Alive > 5 yr |
| 5 2005 |
50 F | MVR | 1.MER | No | Died in hospital < 30 d from diagnosis |
| 6 2008 |
72 M | MV | 1.MER | No | Clinical cure Alive > 1 yr |
| 7 2009 |
58 F | MV | 1.MER + CIP 2.CIP* |
No | Alive > 2 yr |
| 8 2009 |
54M | MV | 1.MER | No | Alive > 5 yr |
| 9 2011 |
80 F | MVR | 1.GEN, MER 2. COL,MER, RIF 3. COL 4. CIP* |
Yes MVR vegectomy |
Died 7 years after episode of i.e. |
| 10 2012 |
75 M | TV + MV | 1.CAZ 2. MER 3. CIP |
No | Died in hospital < 30 d from diagnosis |
| 11 2013 |
52 F IVDU |
AV | 1.TAZ | Yes AVR |
Died from other bacterial, i.e., after < 6 mo |
| 12 2014 |
40 M IVDU |
MV | 1.TAZ 2.MER |
Yes MV repair |
Relapse Alive > 5 yr |
| 13 2017 |
46 M IVDU |
TV | 1.MER + GEN 2.MER + CIP |
Yes TVR |
Clinical cure Alive > 1 yr |
| 14 2017 |
28F | PVR, PC | 1. TAZ | Yes Closure of VSD, redo pulmonary conduit |
Alive > 2 yr No relapse |
| 15 2018 |
45F IVDU |
AVR | 1. TAZ 2. FEP + TOB 3. MER |
No | Died within 6 mo |
AV = aortic valve, AVR = aortic valve replacement, CAZ = ceftazidime. CIP* = ciprofloxacin suppressive therapy, CIP = ciprofloxacin, COL = colistin, GEN = gentamicin, MER = meropenem, MV = mitral valve, MVR = mitral valve replacement, PC = pulmonary conduit, PPM = permanent pacemaker, RIF = rifampicin, TAZ = piperacillin/tazobactam, TIM = ticarcillin/clavulanic, TOB = tobramycin, TV = tricuspid valve, TVR = tricuspid valve replacement, VSD = ventricular septal defect.