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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Nat Immunol. 2023 Jan 19;24(2):309–319. doi: 10.1038/s41590-022-01395-9

Extended Data Fig. 2. T cell subset distribution across tissues and between donors.

Extended Data Fig. 2

Heatmaps illustrating frequency of CD4+ (a) and CD8+ (b) T cell subsets present in each tissue site for all three donors combined and for each individual donor. Color intensity of each cell is based on column z-score values. M, male; F, female; TFH, follicular helper T cell; TRM, tissue-resident memory T cell; gdT, gamma-delta T cell; Treg, regulatory T cell; TCM, central memory T cell; TEMRA, terminally-differentiated effector memory T cell; TEM, effector memory T cell; Th1, type-1 helper T cell; BL, blood; IN, inguinal lymph node; JE, jejunum; LG, lung; LN, lung lymph node; MN, mesenteric lymph node; SK, skin; SP, spleen.