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. 2023 Mar 29;27:82–97. doi: 10.1016/j.bioactmat.2023.03.013

Fig. 6.

Fig. 6

P10G20 proved to be safe after being implanted in the Sprague Dawley rat uterus. a) Scheme showing that P10G20 was injected into one side of the rat uterus. At the chosen time points (Days 3, 4, and 14), the rats were sacrificed, and the uteri were observed. b) Pictures showing the results of rat uteri after hydrogel implantation on days 3, 7, and 14. (Scale bar = 1 cm) c,d) H&E (c) and Masson (d) staining results of the rat uteri on days 3, 7, and 14. (Black scale bar = 400 μm, white scale bar = 50 μm) e) The diameter ratio of the uterus side injected with P10G20 to the healthy side on days 3, 7, and 14. f) The results showing endometrial thickness of uteri after P10G20 implantation as calculated by H&E staining on days 3, 7, and 14. (n = 3, mean ± SD, ns: not significant) g) The results showing the number of endometrial glands of uteri after P10G20 implantation as calculated by H&E staining on days 3, 7, and 14. (n = 3, mean ± SD, ns: not significant) h) The results showing the area of endometrial fibrous tissue of uteri after P10G20 implantation as calculated by Masson staining on days 3, 7, and 14. (n = 3, mean ± SD, ns: not significant). Statistical significance was calculated with Student's t-test in f, g, and h.