Table 2.
Correlations between IRS1 expression and clinical characteristics in patients with GC.
| Variables | Expression of IRS1 | p value | |
|---|---|---|---|
| High (n = 188) | Low (n = 187) | ||
| Age (years) | 0.375 | ||
| Age Mean (SD) | 65.3 (10.2) | 66.3 (11.1) | |
| Age Median [Min Max] | 67 [41 90] | 68 [35 90] | |
| Gender | 0.564 | ||
| Male | 121 (64.36%) | 120 (64.17%) | |
| Female | 67 (35.64%) | 67 (35.83%) | |
| Grade of differentiation | 0.004* | ||
| G1 | 2 (1.06%) | 8 (4.28%) | |
| G2 | 57 (30.32%) | 80 (42.78%) | |
| G3 | 122 (64.89%) | 97 (51.87%) | |
| GX | 7 (3.72%) | 2 (1.07%) | |
| Tumor invasion | 0.012* | ||
| T1 | 2 (1.06%) | 17 (9.09%) | |
| T2 | 35 (18.62%) | 45 (24.06%) | |
| T3 | 84 (44.68%) | 84 (44.92%) | |
| T4 | 61 (32.45%) | 39 (20.86%) | |
| TX | 6 (3.19%) | 2 (1.07%) | |
| Lymph node status | 0.657 | ||
| N0 | 47 (25.13%) | 64 (34.41%) | |
| N1 | 51 (27.27%) | 46 (24.73%) | |
| N2 | 41 (21.93%) | 34 (18.28%) | |
| N3 | 39 (20.86%) | 35 (18.82%) | |
| NX | 9 (4.81%) | 7 (3.76%) | |
| Distant metastasis | 0.982 | ||
| M0 | 165 (87.77%) | 165 (88.24%) | |
| M1 | 13 (6.91%) | 12 (6.42%) | |
| MX | 10 (5.32%) | 10 (5.35%) | |
| TNM stages | 0.155 | ||
| I | 20 (11.36%) | 33 (18.75%) | |
| II | 52 (29.55%) | 59 (33.52%) | |
| III | 83 (47.16%) | 67 (38.07%) | |
| IV | 21 (11.93%) | 17 (9.66%) | |
*Statistically significant. P value < 0.05 are in bold.