Table 2.

Demographic and clinical details.

	Control (n = 30)	PD (n = 29)	p-value
Age (years)	68 ± 1.8 (45–87)	68 ± 1.7 (42–83)	0.92
Sex (% M)	67%	72%	0.64
Years since diagnosis	N/A	6.9 ± 0.8 (0–12)
H&Y stage	N/A	2 ± 0.1 (1–4)
MDS-UPDRS III	N/A	27 ± 3.0 (5–76)
Total alpha-synuclein	12.1 ± 0.9	14.0 ± 1.7	0.32
Hgb (µg/ml)	53.7 ± 7.7	47.4 ± 7.6	0.55
Log10_Total alpha-synuclein (covarying for age, sex and Hgb levels)	1.037 ± 0.034	1.068 ± 0.044	0.689

Demographic and clinical details of the participants who donated the plasma samples used in this study. Data are mean ± standard error, with the range shown in parentheses. Disease severity was recorded using the Hoehn and Yahr (H&Y) scale

MSD-UPDRS Movement disorder society-unified Parkinson's disease rating scale. Hgb Hemoglobin. NA Not applicable.