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. 2023 Mar 17;11:1167586. doi: 10.3389/fchem.2023.1167586

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Copyright © 2023 Li, Li, Li, Zhang, Li, Liu, Lun and Guo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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In vitro cytotoxicity assessment. (A) Viability of 4T1 cells treated with free PB, PB/PM, PB/PM/Apt, PB/PM/HRP/Apt and laser irradiation. (B) Confocal fluorescence images of 4T1 cell viability determined by different treatments. Scale bar: 50 μm. (C) Confocal fluorescence imaging of 4T1 cells treated with PB/PM/Apt at different incubation times. Scale bar: 10 μm. (D) Confocal fluorescence imaging of 4T1 cells treated with PB/PM/HRP/Apt at different incubation times. Scale bar: 10 μm.