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. 2023 Mar 17;14:1137995. doi: 10.3389/fgene.2023.1137995

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Copyright © 2023 Hu, Zhang, Zhang, Huang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunotherapy analysis. (A) The difference of T cell inflamed GEP score among three TME subtypes. (B) The difference of Th1/IFNγ score among three TME subtypes. (C) The difference of Cytolytic activity score among three TME subtypes. (D) Heatmap of immune checkpoints genes among three TME subtypes. (E) the expressions of immune checkpoints genes among three TME subtypes. (F) TIDE analysis among three TME subtypes. (G) The box plots of the estimated IC50 for Paclitaxel, Gemcitabine, Cisplatin, Gefitinib, Mitomycin C, and Sunitinib among three TME subtypes.